The off-label use of medications in cancer care is a growing practice that has garnered attention for its potential to improve patient outcomes. Off-label prescribing refers to the use of a drug for an indication, dosage, or patient population that is not specifically approved by regulatory agencies. In oncology, this practice is prevalent due to the complex nature of cancer, promotion on the internet and through social media, intriguing mechanisms to control cancer, and the limited efficacy of approved therapies particularly in more advanced disease. For integrative healthcare practitioners, understanding this approach and the evidence on which it is based is essential, as patients may present with treatments involving off-label medications and/or be keen on using these therapies as part of their care. This presentation aims to provide an overview of the role of off-label drug use in cancer care, bridging conventional and naturopathic approaches. It will explore both the scientific basis and ethical considerations of this practice, ensuring naturopathic doctors are equipped to collaborate effectively in patient-centered care.
Learning Objectives
- Understand the concept of off-label drug use: Define off-label prescribing in the context of oncology and outline common scenarios where it is applied
- Explore clinical applications: Highlight specific examples of off-label medications used in cancer care and their mechanisms of action
- Examine integrative care opportunities: Discuss how naturopathic doctors can support patients undergoing off-label treatments
- Address challenges and regulations: Assess the ethical, legal, and practical considerations of off-label prescribing, ensuring patient safety and informed decision-making